Nice work. One thing many people are missing here is (1) the quantity of cDNA/EV/plasmid is very high. It should max out at 3 per 1000 RNA (by weight) according to EMA and international standards, but this is looking to be about 1:2 so about 300 per 1000. Having that much plasmid DNA injected into you is really bad - but it gets worse.
The body can normally eradicate plasmid DNA because it's foreign and the DNAases get to work. But this is wrapped in a fluffy LNP transfectant medium, so will get to every cell that the LNP touches. It will transfect the nucleus of those cells, no problem.
So now you have active EV/plasmid DNA in a LNP available to either produce huge quantities of RNA (because that's what they are there for) or else integrate into the genome - which will happen during cell division even in the absence of a specific integrase enzyme.
The quantity available is the deal breaker because it is now present in the same magnitude of amount as the RNA. They might as well have injected the self-amplifying RNA version that they wanted to from the beginning.
Bear in mind that this analysis is just the bivalent, so it's possible that this was a deliberate contamination knowing that there would be no meaningful QA on the product after the regulators completely failed to do any on the original product.
I suppose once they got the trojan horse original "vaxes" through the regulatory process, it would be easier to either 1. dial down your quality control processes for the follow-on varietals (especially if EMA isn't really holding you accountable for your initial gaps) or 2. downright use the lackluster regulations as a mechanism for intentional harm.
You got me thinking tho: the LNP is understood to aid the overall transfection process by getting the payload into the cell (in this case more than just mRNA!), but does the LNP play any role in regards to DNA (from the plasmids) and the nucleus of the cell? Or is the LNP pretty much done (and toxic) once it has gotten the payload into the cell.
OMG... Yes, the LNP... Bypass normal bodily processes of recognition and destruction, and deliver straight into cytoplasm...(and then nucleus) cellular mitosis either doubling amount due to cytoplasmic capture and replication ability of circular plasmids, or contained within nucleus, in which case mitosis transcription error then cancer or autoimmune problems, not to mention systemic interference in normal cellular processes... I hope I read this right?? (or maybe I hope I haven't read this right, I'm praying that I have it wrong here, as this could be a bigger disaster than we've already seen worldwide)
anandamide did guess it is enough to infect 0,1% of our cells "in an inheritable fashion", i.e., when the cell clones, it does a copy of the plasmids ring like it copies every organelle like mitochondria etc.. So both sibling cells get each a copy of it. Do not know if there are variations in mitosis that enhance or decrease chance of passing-on, if it is 1:1 or can vary. These would be the true treasures for curing.
Right now you just have to soothe immune system to endure the high load of foreign mRNA producing captured cells without letting it slip too much into "desensitized" mode, as mRNA/Spike desensitization means severe viral load upon infection and other maladies.
Another problem arises: as all vaccinated are desensitized to some degree, they do not understand how tiny amounts of shedding bear a high load on the unvaccinated, further dividing the people.
Solution is that bothgrous (and the grey in-between like children of vaccinated parents, being a little bit vaccinated) do regular detox "cure-lets" like 2x per week some systemic oxidative intervention (as simple as drinking 10x a day a gulp of 1L/day of some CDS water.
(I do 1/3 of NOAEL=3mg/kg/day, distributed over the day; NOAEL: No Observeable Events Level (of dosing) of CIO2(aq) 0,3% ca. 25ml per 1L water and drink it over the day, every time the stomach is empty and next meal is ca. 1/2 hr away at least.)
Don't forget some healing earth or ceolite or mixed later. Oxidatives bring toxins like heavy metals in circulation, you want something to bind them and get them out.
Re-Regulate epigenetic by herbal and other interventions "swing cure", massaging the immune system back to pre-traumatic state.
(I try using different herbs and mushroom extract and choose something like a "combo of the week", and choose a different one next week. It is based on searches for phytotherapy epigenetic regulative etc., but done "instinctively". I have no time to further research. The vaccine is gnawing me from the insides, many new autoantibodies, on binding tissue, and nerve endings a bit...)
Great question. I wrote that thread prior to reading up on the much broader vaccine questions. In short, NO. I consider myself, with some exceptions, an exvaxxer now.
I'd like to say: I think my stupid stoned ass tried to sign into your account by just clicking stuff. I was trying to sign into my account and subscribe. If you get some kind of notification about an attempted login, it's me accidently clicking the wrong stuff. I was not paying much attention and just hit a sign in button from your page, then used my email. Now I have a "sign into clownbasket" email sitting in my trash bin. Super duper sorry, and no reason to freak. Idk who you are but I am just here for the dumbed down version of Kevin's stuff because I don't have time to understand everything he wrote, I promise. Pls forgive me, super duper sorry. I don't use substack well, or often. I've only signed in a few times so I haven't paid much attention to the process
Awesome work! Thank you. I love it when people do this (with images!) because it makes it so much easier and faster for me to get the ideas out for a wider audience on social media.
Easier to say "Houston we have a major problem and here's why..."
Also Eureka! Thanks for mentioning Dr VSK! Her interview is the most shared link I've posted on Twitter and what earned my first account @Janieyaya permanent suspension in 2021. I STILL point people to that interview, as it seemed highly predictive then and now prescient. Thanks for your hard work explaining the complex genetics science. I'm suspended @ssayssayssay again on Twitter but will put this out on the other sm sites. Keep going!!
I actually understood 95% of this. Thank you! There's another part I don't understand...and I guess it's because I thought we already knew the vax caused autoimmune or inflammatory conditions and cancer. I don't understand why this is different. Anything by Kevin was very hard to understand as well.
In some ways it is similar, with plamids in the vax the body could kick off an immune response to address the threats. Inflammation could result. But the difference here is the possibility of the plasmid DNA integrating into the human DNA. It is unlikely but it is theoretically possible.
Thank you for the reply. I was reading some comments on Kevin's substack, because I hoped that many different point of views could help and one commenter explained it so I could grasp it a bit more. It reminded me of the scene from Jurassic Park, where Alan says to the kids, "They filled the gaps in the dinosaurs' genome with frog DNA..."
We didn't have gaps in our genome, but the mRNA can be input into our genome. And it's an antibiotic bacteria resistant DNA. I am staggered all of a sudden at what that means.
The Pfizer jabs have an "acceptable" upper limit of 12.5 EU/ml which is known to be Lethal in some unfortunate Jabbees. Pfizer won't release individual Endotoxin measurements in different Lots or Batches. We do know they had at least large production run that exceeded the limit.
My understanding is an origin of replication in a bacterial plasmid allows for replication in bacterial cells but not human cells. For replication in human cells you need a human origin of replication. Perhaps you can check this as this is not my field.
As for integration this has been studied with DNA vaccines. The conclusion as I recall was that integration frequency was typically less than your DNA’s spontaneous mutation rate by up to 3 orders of magnitude. Of course, FDA requires integration studies for DNA vaccines, something Pfizer does not due as DNA is assumed to be negligible
Keep in mind most cells transfected are killed by immune cells, which is enhanced by the interferon response the dsDNA induces
The question is why is the circular DNA resisting linear linearization by the restriction enzyme and why is the DNA (circular of linear) resisting DNase degradation.
How is it possible to use 2 different plasmids (diff expression vectors) in one lot. Does Pfizer have multiple sources of plasmids (Agilent is one source that was recruited in 2021 suggesting there are at least 2)? Even them my understanding is each batch from a 37.5 L vat has its own unique lot number.
Has anyone checked the Lot numbers against VAERS to see if they are hot lots?
The origin of replication is a bacterial origin of replication. I doubt the vector will replicate in mammalian cells unless integrated. However, it can replicate in bacteria and the bactofection literature should give us pause. If bacteria perform the amplification and release these into mammalian cells via bactofection we could see T7 expression in the mammalian cell. https://pubmed.ncbi.nlm.nih.gov/14566363/
Not much bacteria to be found within the circulatory system though. How much of the mRNA/DNA lipid package make it to the intestine? I haven't seen that reported. I suppose that could be a problem (increased colon cancer?)
Thank you for breaking this down. I understand it now. Is this why some of the vaccine injured continue to get worse? Because their body sees their cells as foreign and attacks them? I’m also curious about different batches. We know that some batches had more lipids in them? Is it possible that some batches had more of the bacteria plasmids?
Why is Clownbasket pro-test if the tests are garbage? The primers were created in the absence of a sample. If you don’t understand that the testing is fraudulent, you don’t know much-?
If you are referring to the language in my 2021 tweet then you are not interpreting it correctly. Are you assuming “pro-test” means pro PCR test? If so that is an incorrect assumption. In that 2021 tweet I was referring to the test process for vaccine development, production and distribution. I believe if you read the thread that becomes obvious.
Do those plasmid DNA fragments generate bacterial/viral peptides that will attract immunity or activate T killer cells? Are they immunogenic? What will happen if they are integrated into the genome of cells? Will those cells get killed off?
Great stuff! You beat me to the compendium of how to make a shit-ton of mRNA. Still gonna write it up though. :)
Nice work. One thing many people are missing here is (1) the quantity of cDNA/EV/plasmid is very high. It should max out at 3 per 1000 RNA (by weight) according to EMA and international standards, but this is looking to be about 1:2 so about 300 per 1000. Having that much plasmid DNA injected into you is really bad - but it gets worse.
The body can normally eradicate plasmid DNA because it's foreign and the DNAases get to work. But this is wrapped in a fluffy LNP transfectant medium, so will get to every cell that the LNP touches. It will transfect the nucleus of those cells, no problem.
So now you have active EV/plasmid DNA in a LNP available to either produce huge quantities of RNA (because that's what they are there for) or else integrate into the genome - which will happen during cell division even in the absence of a specific integrase enzyme.
The quantity available is the deal breaker because it is now present in the same magnitude of amount as the RNA. They might as well have injected the self-amplifying RNA version that they wanted to from the beginning.
Bear in mind that this analysis is just the bivalent, so it's possible that this was a deliberate contamination knowing that there would be no meaningful QA on the product after the regulators completely failed to do any on the original product.
I suppose once they got the trojan horse original "vaxes" through the regulatory process, it would be easier to either 1. dial down your quality control processes for the follow-on varietals (especially if EMA isn't really holding you accountable for your initial gaps) or 2. downright use the lackluster regulations as a mechanism for intentional harm.
You got me thinking tho: the LNP is understood to aid the overall transfection process by getting the payload into the cell (in this case more than just mRNA!), but does the LNP play any role in regards to DNA (from the plasmids) and the nucleus of the cell? Or is the LNP pretty much done (and toxic) once it has gotten the payload into the cell.
OMG... Yes, the LNP... Bypass normal bodily processes of recognition and destruction, and deliver straight into cytoplasm...(and then nucleus) cellular mitosis either doubling amount due to cytoplasmic capture and replication ability of circular plasmids, or contained within nucleus, in which case mitosis transcription error then cancer or autoimmune problems, not to mention systemic interference in normal cellular processes... I hope I read this right?? (or maybe I hope I haven't read this right, I'm praying that I have it wrong here, as this could be a bigger disaster than we've already seen worldwide)
So what happens if it gets into the nucleus ?
anandamide did guess it is enough to infect 0,1% of our cells "in an inheritable fashion", i.e., when the cell clones, it does a copy of the plasmids ring like it copies every organelle like mitochondria etc.. So both sibling cells get each a copy of it. Do not know if there are variations in mitosis that enhance or decrease chance of passing-on, if it is 1:1 or can vary. These would be the true treasures for curing.
Right now you just have to soothe immune system to endure the high load of foreign mRNA producing captured cells without letting it slip too much into "desensitized" mode, as mRNA/Spike desensitization means severe viral load upon infection and other maladies.
Another problem arises: as all vaccinated are desensitized to some degree, they do not understand how tiny amounts of shedding bear a high load on the unvaccinated, further dividing the people.
Solution is that bothgrous (and the grey in-between like children of vaccinated parents, being a little bit vaccinated) do regular detox "cure-lets" like 2x per week some systemic oxidative intervention (as simple as drinking 10x a day a gulp of 1L/day of some CDS water.
(I do 1/3 of NOAEL=3mg/kg/day, distributed over the day; NOAEL: No Observeable Events Level (of dosing) of CIO2(aq) 0,3% ca. 25ml per 1L water and drink it over the day, every time the stomach is empty and next meal is ca. 1/2 hr away at least.)
Don't forget some healing earth or ceolite or mixed later. Oxidatives bring toxins like heavy metals in circulation, you want something to bind them and get them out.
Re-Regulate epigenetic by herbal and other interventions "swing cure", massaging the immune system back to pre-traumatic state.
(I try using different herbs and mushroom extract and choose something like a "combo of the week", and choose a different one next week. It is based on searches for phytotherapy epigenetic regulative etc., but done "instinctively". I have no time to further research. The vaccine is gnawing me from the insides, many new autoantibodies, on binding tissue, and nerve endings a bit...)
Wait, did Kevin McKernan mention if those plasmid DNA he observed are inside the LNP or just floating in the water?
I think they testet it by using the protective properties the LNP shell offers and killed the DNA outsides of the LNPs.
Thank you for this. One question, are you still pro vax??
Great question. I wrote that thread prior to reading up on the much broader vaccine questions. In short, NO. I consider myself, with some exceptions, an exvaxxer now.
Exvaxxer!! Love that new word. I may use it if I may
I stole it myself. People were using it in replies to my pinned Tweet.
Amazing writeup!!
I'd like to say: I think my stupid stoned ass tried to sign into your account by just clicking stuff. I was trying to sign into my account and subscribe. If you get some kind of notification about an attempted login, it's me accidently clicking the wrong stuff. I was not paying much attention and just hit a sign in button from your page, then used my email. Now I have a "sign into clownbasket" email sitting in my trash bin. Super duper sorry, and no reason to freak. Idk who you are but I am just here for the dumbed down version of Kevin's stuff because I don't have time to understand everything he wrote, I promise. Pls forgive me, super duper sorry. I don't use substack well, or often. I've only signed in a few times so I haven't paid much attention to the process
Awesome work! Thank you. I love it when people do this (with images!) because it makes it so much easier and faster for me to get the ideas out for a wider audience on social media.
Easier to say "Houston we have a major problem and here's why..."
Also Eureka! Thanks for mentioning Dr VSK! Her interview is the most shared link I've posted on Twitter and what earned my first account @Janieyaya permanent suspension in 2021. I STILL point people to that interview, as it seemed highly predictive then and now prescient. Thanks for your hard work explaining the complex genetics science. I'm suspended @ssayssayssay again on Twitter but will put this out on the other sm sites. Keep going!!
I actually understood 95% of this. Thank you! There's another part I don't understand...and I guess it's because I thought we already knew the vax caused autoimmune or inflammatory conditions and cancer. I don't understand why this is different. Anything by Kevin was very hard to understand as well.
In some ways it is similar, with plamids in the vax the body could kick off an immune response to address the threats. Inflammation could result. But the difference here is the possibility of the plasmid DNA integrating into the human DNA. It is unlikely but it is theoretically possible.
In other words, humans could become part e. coli? What a prospect.
Thank you for the reply. I was reading some comments on Kevin's substack, because I hoped that many different point of views could help and one commenter explained it so I could grasp it a bit more. It reminded me of the scene from Jurassic Park, where Alan says to the kids, "They filled the gaps in the dinosaurs' genome with frog DNA..."
We didn't have gaps in our genome, but the mRNA can be input into our genome. And it's an antibiotic bacteria resistant DNA. I am staggered all of a sudden at what that means.
Very helpful thankyou, this helps cement my understanding from the original Anandamide article.
Jessica also helped to show how bad this could be.
A big thank you for breaking down this technical material for us laymen.
Could the reason why Ivermectin works for Covid be that the circular DNA is from bacteria, and Ivermectin acts on bacteria?
Did someone mention E coli Endotoxins?
The Pfizer jabs have an "acceptable" upper limit of 12.5 EU/ml which is known to be Lethal in some unfortunate Jabbees. Pfizer won't release individual Endotoxin measurements in different Lots or Batches. We do know they had at least large production run that exceeded the limit.
https://geoffpain.substack.com/p/endotoxins-in-pfizer-jabs-mimic-nickel
Interesting.
My understanding is an origin of replication in a bacterial plasmid allows for replication in bacterial cells but not human cells. For replication in human cells you need a human origin of replication. Perhaps you can check this as this is not my field.
As for integration this has been studied with DNA vaccines. The conclusion as I recall was that integration frequency was typically less than your DNA’s spontaneous mutation rate by up to 3 orders of magnitude. Of course, FDA requires integration studies for DNA vaccines, something Pfizer does not due as DNA is assumed to be negligible
Keep in mind most cells transfected are killed by immune cells, which is enhanced by the interferon response the dsDNA induces
The question is why is the circular DNA resisting linear linearization by the restriction enzyme and why is the DNA (circular of linear) resisting DNase degradation.
How is it possible to use 2 different plasmids (diff expression vectors) in one lot. Does Pfizer have multiple sources of plasmids (Agilent is one source that was recruited in 2021 suggesting there are at least 2)? Even them my understanding is each batch from a 37.5 L vat has its own unique lot number.
Has anyone checked the Lot numbers against VAERS to see if they are hot lots?
The origin of replication is a bacterial origin of replication. I doubt the vector will replicate in mammalian cells unless integrated. However, it can replicate in bacteria and the bactofection literature should give us pause. If bacteria perform the amplification and release these into mammalian cells via bactofection we could see T7 expression in the mammalian cell. https://pubmed.ncbi.nlm.nih.gov/14566363/
Not much bacteria to be found within the circulatory system though. How much of the mRNA/DNA lipid package make it to the intestine? I haven't seen that reported. I suppose that could be a problem (increased colon cancer?)
Thank you for breaking this down. I understand it now. Is this why some of the vaccine injured continue to get worse? Because their body sees their cells as foreign and attacks them? I’m also curious about different batches. We know that some batches had more lipids in them? Is it possible that some batches had more of the bacteria plasmids?
Why is Clownbasket pro-test if the tests are garbage? The primers were created in the absence of a sample. If you don’t understand that the testing is fraudulent, you don’t know much-?
If you are referring to the language in my 2021 tweet then you are not interpreting it correctly. Are you assuming “pro-test” means pro PCR test? If so that is an incorrect assumption. In that 2021 tweet I was referring to the test process for vaccine development, production and distribution. I believe if you read the thread that becomes obvious.
Do those plasmid DNA fragments generate bacterial/viral peptides that will attract immunity or activate T killer cells? Are they immunogenic? What will happen if they are integrated into the genome of cells? Will those cells get killed off?
Thank you, slowly getting my head around the basics of something that is so complex